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Cyclobenzaprine: What It Is and What’s Too Much Addiction Treatment

News & Blog

Cyclobenzaprine: What It Is and What’s Too Much Addiction Treatment

Medicines that interact with Flexeril may either decrease its effect, affect how long it works, increase side effects, or have less of an effect when taken with Flexeril. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Speak to your doctor about how drug interactions should be managed. Acetaminophen is used to relieve pain and reduce fever in patients. But acetaminophen may cause other unwanted effects when taken in large doses, including liver damage.

  • Cyclobenzaprine is one of the most studied skeletal muscle relaxants, with solid evidence and systematic reviews supporting its effectiveness.
  • Abrupt discontinuation of these drugs after long-term use can cause withdrawal symptoms.
  • Flexeril contains cyclobenzaprine and is available in an extended-release form that can be taken once per day.

Zanaflex has the potential to cause hypotension or abnormally low blood pressure. This effect typically manifests as orthostatic hypotension which occurs when a person moves to an upright position after lying down. In excess doses, Flexeril is also known to cause changes in blood pressure. It’s necessary to take cyclobenzaprine exactly as directed by your doctor to ensure safe usage.

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These medications should only be taken if their benefits outweigh the risks. Muscle relaxants should only be taken with medical guidance from a doctor. Since Robaxin and Flexeril have CNS depressant effects, they can interact with other drugs that have similar effects. Drugs that have CNS depressant effects include barbiturates and benzodiazepines.

It works in the central nervous system (CNS) to relieve muscle pain and spasms. Cyclobenzaprine is available in immediate-release and extended-release forms. Now, skeletal muscle relaxants can further be divided into centrally-acting and direct-acting muscle relaxants.

Zanaflex only comes in immediate-release oral tablets and capsules while Flexeril comes in an extended-release capsule. Flexeril is known to cause serotonin syndrome, especially when taken with certain antidepressants, MAO inhibitors, and opioids. Signs and symptoms of serotonin syndrome should be monitored when starting treatment with Flexeril. Like other muscle relaxants, Zanaflex and Flexeril work in the central nervous system (CNS). Seek medical attention if symptoms of hepatic failure occur during therapy with this agent. 5 mg 3 times daily; may increase dosage to 10 mg 3 times daily depending on response.

Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly. However, severe withdrawal side effects can usually be prevented by gradually reducing the dose over a period of time before treatment is stopped completely. Flexeril is one of the most studied muscle relaxants; thus, it has more supporting evidence for its effectiveness. In a systematic review, it was found that, in general, muscle relaxants are comparable in effectiveness. This review included other muscle relaxants such as metaxalone, baclofen, tizanidine, orphenadrine, and chlorzoxazone. Robaxin and Flexeril are FDA approved to treat discomfort or muscle spasms from acute musculoskeletal conditions as well as tetanus.

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Generic methocarbamol is around $6.25 for 30 tablets of the 500mg dose with a BuzzRx drug discount card. Brand name Robaxin is approximately $95 for 30 tablets of the 750mg dose with a BuzzRx savings card. Generic cyclobenzaprine may be under $0.50 for 30 tablets of the 10mg dose through the BuzzRx discount program. Methocarbamol can be used for long or short-term treatment as advised by a doctor. On the other hand, cyclobenzaprine is generally not prescribed for longer than two or three weeks.

Cyclobenzaprine is a skeletal muscle relaxant that works on the brainstem to treat muscle spasms of local origin. Methocarbamol and cyclobenzaprine are not recommended in elderly adults. Both medications are on the BEERS list, a recognized list of medications prepared by the American Geriatrics Society. Muscle relaxants with CNS depressant effects can increase the risk of dizziness, falls, and serious injury in the elderly. Flexeril has also been studied to treat fibromyalgia, a chronic condition characterized by muscle pain all over the body.

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Also, cyclobenzaprine can cause dry mouth because it has anticholinergic effects. The risk of serious side effects and overdose from cyclobenzaprine increases when dangerous flexeril and wellbutrin drug interactions occur. Patients should tell their doctors about any other prescriptions they’re taking before ingesting a muscle relaxant like cyclobenzaprine.

It is usually taken as a 2 mg or 4 mg tablet every six to eight hours. Overall, the study found that these drugs are comparable in efficacy and safety. Other guidelines suggest that muscle relaxants cause increased drowsiness and should only be used short-term. According to a meta-analysis, cyclobenzaprine has been studied in the most clinical trials with evidence to support its use. Tizanidine was shown to be effective for spasticity due to multiple sclerosis.

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